
Dr Matthias Bruhn awarded doctoral prize by the HZI Förderverein
Award ceremony as part of the Inhoffen Lecture on 13 June 2024
Here you can gain an insight into the projects of the Kalinke Lab in the field of immunology. In particular, immune responses in acute hepatitis and encephalitis are being investigated in order to develop innovative therapies on this basis.
The project investigates how HCMV is recognized by the immune system and which mechanisms the virus uses to camouflage itself. The aim is to understand the immune reactions and develop therapies for severely affected patients.
The project investigates immune reactions in viral hepatitis, in particular the role of hepatocytes and myeloid cells. The aim is to understand immune processes in the liver and to develop diagnostic approaches for the clinic.
The project investigates the immune response of the central nervous system in viral infections, in particular the role of type I IFN, microglia and monocytes in the development of encephalitis and their influence on seizures and hippocampal damage.
The project will investigate the immunological and genetic causes of vaccination failure in 5% of HBV-vaccinated individuals in order to develop new strategies to improve vaccination protection.
The project is developing methods to specifically transport antibiotics into cells such as alveolar macrophages, which are important in Mycobacterium tuberculosis infections. The aim is to overcome resistance and reduce side effects.
The project is developing iPSC-based therapies for MSMD patients, a genetic disease with mutations in the IFN-γ signaling pathway that lead to severe mycobacterial infections. The aim is to improve the treatment prognosis.
Award ceremony as part of the Inhoffen Lecture on 13 June 2024
TWINCORE scientist honoured for outstanding doctoral thesis.
MEMUMAB research project receives GO-Bio initial funding / Kickoff on 22 November
A research team at TWINCORE was able to establish that TLR8 influences the formation of disease-relevant cytokines.
TWINCORE researchers show role of epistatic interaction in the omicron variant of SARS-CoV-2 virus .
How B cells recognise new variants of SARS-CoV-2
HCMV reprograms cellular defence mechanisms
TWINCORE researchers describe how birch pollen affects immune cells
Communication between immune cells determines response to vaccination
How immune cells are lured to the brain in encephalitis
New transport route for antibiotics directly into infected cells
TWINCORE scientists decode a new camouflage mechanism of cytomegalovirus
Researchers in Hannover have developed a new method for studying neuroinfections.
Clinician scientist Theresa Graalmann starts her own group at TWINCORE