
Project manager of the immune defence in the brain
How immune cells in the brain coordinate their work
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
This year's symposium will take place on 18 and 19 September in collaboration with SLS Europe.
How immune cells in the brain coordinate their work
New insights into the infection strategy of Pseudomonas aeruginosa
Research team from Bochum and Hannover shows that the hepatitis E virus also attacks organs other than the liver
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
Bartsch Y, Webb N, Burgess E, Kang J, Lauffenburger D, Julg B
Buttler L, Velázquez-Ramírez D, Tiede A, Conradi A, Woltemate S, Geffers R, Bremer B, Spielmann V, Kahlhöfer J, Kraft A, Schlüter D, Wedemeyer H, Cornberg M, Falk C, Vital M, Maasoumy B
Lynch-Miller M, Lockow S, Dümmer K, Henneck T, Olmer R, Jaboreck M, Mergani A, Wandrey M, Branitzki-Heinemann K, Brogden G, Naim H, Martin U, Schulz C, Talbot S, Meurer M, Baumgärtner W, von Köckritz-Blickwede M
The project investigates the immune response of the central nervous system in viral infections, in particular the role of type I IFN, microglia and monocytes in the development of encephalitis and their influence on seizures and hippocampal damage.
We are investigating why HCV infections sometimes heal spontaneously, but often become chronic, and why RSV infections are severe in some children. We use modern sequencing technologies to analyze the genetic characteristics of hosts and pathogens in order to understand susceptibility.
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
Thanks to high-throughput sequencing, genome sequences of hundreds of bacterial strains can be analyzed efficiently, revealing differences of up to 60 % in gene content, as in E. coli. With the help of machine learning, we want to better predict the functions of accessory genes and decipher their contribution to survival in specialized niches.
There are currently no events.