AI in Research and Administration
TWINCORE establishes task force
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Hepatology (baltimore, Md.) : 10.1097/HEP.0000000000001769
Two decades of Hepatitis E in solid organ transplantation: From endemic insight to unresolved therapeutic questions
Behrendt P, Neumann-Haefelin C
2026Science Advances12 (14) : eaeb2333
Hepatitis E virus replication is maintained in proliferative cells within the intestinal crypt
Prallet S, Maier N, Li A, Afting C, Huang H, Hu J, Toprak E, Keya D, Colasanti O, León-Janampa N, Marlet J, Beisel C, Mogler C, Puchas P, Behrendt P, Boettler T, Steinmann E, Saha S, Laketa V, Lohmann V, Wittbrodt J, Hermann C, Dill M, Dao Thi V
2026Nature Immunology : 10.1038/s41590-026-02472-z
A transcriptomic microglia taxonomy across mouse and human pathologies
Chhatbar C, Sankowski R, Schulz M, Shimizu T, Schwabenland M, Staszewski O, Scheiwe C, Nessler S, Borst K, Dumas A, Trost E, Berchtold D, Brandão W, Mossad O, Dalmau Gasull A, Frosch M, Erny D, Diebold M, Guffart E, Ternka K, Guranda M, Vinnakota J, Friesen M, Ouk K, Waltl I, LaMorte M, Hammond T, Di Liberto G, Vincenti I, Kreutzfeldt M, Mughrabi I, Al-Abed Y, Blank T, Meyer-Luehmann M, Crow Y, Hagen N, Ofengeim D, Zeiser R, Kettwig M, Gärtner J, Meisel A, Schwemmle M, Kalinke U, Beck J, Bengsch B, Thimme R, Butovsky O, Seredenina T, Ransohoff R, Quintana F, Kierdorf K, Merkler D, Stadelmann C, Priller J, Prinz M
Graalmann Lab
Immunology
Tissue inflammation upon chronic rheumatic diseases
Patients with chronic rheumatic diseases have an increased risk of infection due to severe inflammation. This project investigates inflammation in various tissues, particularly in systemic sclerosis, in order to develop targeted therapies.
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Lauber Lab
Virology
Deep exploration of the virosphere for novel viruses in humans and other eukaryotes
Using high-performance computers, we analyze NGS data to discover unknown viruses in the human and animal virome that could influence disease risks. We investigate the virome as a factor for infections and diseases such as cancer and immunodeficiencies.
Galardini Lab
Bacteriology
Genotype to phenotype studies in bacteria
By applying statistical genetics methods to pathogen genome sequences, we aim to identify and validate genetic determinants of phenotypes such as pathogenicity, virulence and antibiotic resistance, e.g. in E. coli and P. aeruginosa.
A practical guide to vibe engineering
The seminar covers the principles and tools of "vibe engineering" for using AI coding agents to solve digital problems. Participants will learn how to leverage these agents while understanding and mitigating associated risks to data and intellectual property. The session includes practical examples and guidance for safe implementation.
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
