Future Day 2026 at TWINCORE
Eleven pupils gain an insight into infection research
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Aids (london, England) : 10.1097/QAD.0000000000004529
HIV immunological non-responders show low SKAP1 concentration and DNA hypermethylation in the SKAP1 promotor region: Low Skap1 in HIV Immunological Non-Responders
Vos W, De Ruijten S, Jiang X, van Unen N, van Snippenberg W, Groenendijk A, Blaauw M, Eekeren L, Vadaq N, Maas H, Östman M, Cleophas M, Brinkman K, van Lunzen J, Blok W, Stalenhoef J, Li Y, Netea M, Vandekerckhove L, Dos Santos J, Matzaraki V, Xu C, Ven A
2026Science Immunology11 (118) : eadw7077
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M, Bender A, Vöcking L, Richter M, Hageb A, Suerdieck V, Arenas Cerro F, Braster Q, Guzman M, Sintes J, Sharma S, Lemnitzer P, Tulotta C, Börgeling Y, Herrero-Cervera A, Flueter H, Reinartz Groba S, Ahern D, Osei-Sarpong C, Zimmer R, Alonso-Gonzalez N, Ortega E, Lienenklaus S, Kalinke U, Ludwig S, Engel D, Rosenbauer F, Monaco C, Dersch P, Kibler A, Cerutti A, Chavakis T, Benedito R, Hidalgo A, Jablonska J, Palomino-Segura M, Soehnlein O
2026Cell Genomics : 101218
Interferon-related inflammaging links epigenetic age acceleration to multimorbidity
Liu Z, Ziogas A, Zhang Y, Gupta M, Föhse K, Taks E, Dulfer E, Sarlea A, Ventriglia L, Geckin B, Ballan M, van Unen N, Helder L, Trittel S, Riese P, Moorlag S, de Bree C, Koeken V, Mourits V, Jaeger M, Pessler F, Guzmán C, Joosten L, Li Y, Xu C, Netea M
Graalmann Lab
Immunology
Cell-selective targeting of immune cells
Immunomodulatory drugs can have systemic side effects. This project is testing nanocarriers that deliver drugs specifically into myeloid immune cells in order to reduce side effects and increase the local effect.
Pessler Lab
Immunology
Cerebrospinal fluid biomarkers for early diagnosis and risk stratification of CNS infections
In collaboration with the Department of Neurology and the Metabolomics Department, the project is investigating metabolic products in cerebrospinal fluid in order to identify biomarkers for CNS infections and cell damage and to distinguish long COVID and viral from autoimmune diseases.
Pessler Lab
Immunology
Functional Biomarkers for respiratory infections
This project focuses on lung infections such as influenza, COVID-19, pneumonia and tuberculosis in order to improve diagnostics, patient stratification and therapy. RNA molecules and metabolites are being investigated as biomarkers and complementary therapies.
Behrendt Lab
Virology
Prevention of HEV Infection
Studies in the cell culture model show that only a few disinfectants are effective against HEV, which provides important information on hygiene measures for HEV infections. We are also working together to test vaccines for pigs as HEV reservoirs.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Lecture Series - Regulatory Science and Translational Research - Part 1
"Why is knowledge in regulatory science important for translational medicine and basic science?"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
