Season's Greetings
TWINCORE wishes you happy holidays and a successful new year
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Infection and Immunity : e0045325
Pseudopaline-mediated zinc uptake by Pseudomonas aeruginosa drives clinically relevant phenotypes and infection outcomes
Bosc L, Sécher T, Ball G, Le Pennec D, Tribout M, Ba M, Bai Y, Ouerdane L, Arnoux P, Denis Y, Lei X, Bordi C, Heuzé-Vourc'h N, Häussler S, Gomez N, Voulhoux R
2026Respiratory Research : 10.1186/s12931-026-03497-6
Clinical implications of traction bronchiectasis in IPF and fibrotic RA-ILD - a retrospective single-center cohort study
Raith J, Ruwisch J, Schupp J, Graalmann T, Drick N, Hoeper M, Prasse A, Fuge J, Ringshausen F, Knegendorf L, Rademacher J, Dettmer S, Seeliger B
2026Acta Biomaterialia : S1742-7061(26)00026-7
Commensal microflora coating endows implants with biofilm-repellent, immunomodulatory and osteogenic properties
Rahim M, Baseer S, Paasch D, Steglich M, Waqas S, Lachmann N, Falk C, Stiesch M
Graalmann Lab
Immunology
Indirect effects of immunomodulatory drugs
Immunomodulatory drugs for rheumatic diseases specifically influence immune cells and messenger substances. This project investigates their effect on immune responses in order to find individually suitable therapies.
Bartsch Lab
Immunology
Harnessing antibody Fc effector functions as therapeutic target
The project is researching how the effect of monoclonal antibodies can be improved. These antibodies are already being used successfully against viruses. The aim is to optimize the so-called Fc effector functions in order to fight infections even more effectively.
Pessler Lab
Immunology
Cerebrospinal fluid biomarkers for early diagnosis and risk stratification of CNS infections
In collaboration with the Department of Neurology and the Metabolomics Department, the project is investigating metabolic products in cerebrospinal fluid in order to identify biomarkers for CNS infections and cell damage and to distinguish long COVID and viral from autoimmune diseases.
Lauber Lab
Virology
Pandemic preparedness: assessing spill-over risk of RNA viruses
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
There are currently no events.
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
