AI in Research and Administration
TWINCORE establishes task force
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Journal of Clinical Microbiology : e0104425
Genomic epidemiology of Enterococcus faecium bloodstream infections during a VanB-type VRE peak reveals an oligoclonal scenario: an observational study at a German university hospital (2017-2022)
Knegendorf L, Sommer A, Baier C, Weber R, Fischer M, Werner G, Ziesing S, Schlüter D
2026International Journal of Cancer : 10.1002/ijc.70427
ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance
Sánchez-Maldonado J, Macauda A, Cabrera-Serrano A, Thomsen H, Güler M, Horst R, van Guelpen B, Vodicka P, Landi S, Chattopadhyay S, Ünal P, Ruiz-Durán L, Casabonne D, Goldschmidt H, Serin I, Carretero-Fernández M, Cabezudo E, Reyes-Zurita F, Norman A, García-Sanz R, Capurso G, Hoffmann P, Pettersson-Kymmer U, Jiménez-Romera F, Rajkumar S, Weinhold N, Vodickova L, Langer C, Stein A, Karismaz A, Moreno V, Nöthen M, Jöckel K, Tavano F, Martínez-López J, Kumar S, Gutiérrez-Bautista J, Basso D, Späth F, Benavente Y, Hildebrandt M, Schmidt B, Sevcikova T, Reis R, Li Y, López-Nevot M, Netea M, Campa D, Clay-Gilmour A, Slager S, Hemminki K, Vachon C, Försti A, Canzian F, Sainz J
2026Communications Biology : 10.1038/s42003-026-09724-6
NRF2 activators and the inhibitor of nuclear export, selinexor, restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1 through an NRF2-independent mechanism
Waqas F, S da Costa L, Zapatero-Belinchón F, Carter-Timofte M, Lasswitz L, van der Horst D, Möller R, Dahlmann J, Olmer R, Geffers R, Gerold G, Olagnier D, Pessler F
Graalmann Lab
Immunology
Tissue inflammation upon chronic rheumatic diseases
Patients with chronic rheumatic diseases have an increased risk of infection due to severe inflammation. This project investigates inflammation in various tissues, particularly in systemic sclerosis, in order to develop targeted therapies.
Graalmann Lab
Immunology
Cell-selective targeting of immune cells
Immunomodulatory drugs can have systemic side effects. This project is testing nanocarriers that deliver drugs specifically into myeloid immune cells in order to reduce side effects and increase the local effect.
Pessler Lab
Immunology
Functional Biomarkers for respiratory infections
This project focuses on lung infections such as influenza, COVID-19, pneumonia and tuberculosis in order to improve diagnostics, patient stratification and therapy. RNA molecules and metabolites are being investigated as biomarkers and complementary therapies.
Lauber Lab
Virology
Pandemic preparedness: assessing spill-over risk of RNA viruses
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
Seminar
TWINCORE Seminar
Prof. Dr. Niels Lemmermann
Institut für Virologie
Universitätsklinikum Bonn
“From Virus to T Cells: Antigen Presentation During mCMV Infection”
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
A practical guide to vibe engineering
The seminar covers the principles and tools of "vibe engineering" for using AI coding agents to solve digital problems. Participants will learn how to leverage these agents while understanding and mitigating associated risks to data and intellectual property. The session includes practical examples and guidance for safe implementation.
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
