Christine Ehlers receives PhD Prize of the Gesellschaft der Freunde der MHH
The 23rd doctoral thesis to receive an award at TWINCORE
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Science Advances12 (19) : eaeb5967
The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis
Ruwisch J, Cazes A, Leiber L, Borie R, Neubert L, Christian L, Thomas de Montpréville V, Szmul A, Moussa F, Verleden S, Gaedcke S, Hegermann J, Fuge J, Ballmaier M, Kamp J, Greer M, Braubach P, Werlein C, Ius F, Graalmann T, Aburahma K, De Sadeleer L, Egashira R, Ackermann M, Yamada D, Hoeper M, Falk C, Gottlieb J, Schiller H, Vanaudenaerde B, Seeliger B, Debray M, Bernaudin J, Knudsen L, Bergot E, Jacob J, Mal H, Jonigk D, Dettmer S, Mordant P, Prasse A, Fadel E, Wuyts W, Crestani B, Kaminski N, Justet A, Schupp J
2026Journal of Virology : e0034226
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
Hahlin E, Danskog K, Nord S, Becker M, Willekens S, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
2026Frontiers in Immunology17 : 1637735
Identification of new overlapping and disease-specific genetic risk factors for rheumatoid arthritis and radiographic axial spondyloarthritis: a meta-analysis of three large European populations and functional characterization
Cabrera-Serrano A, Carretero-Fernández M, Pérez-Rojo B, Ter Horst R, Cañadas-Garre M, Canhão H, Quartuccio L, Sorensen S, Glintborg B, Filipescu I, Pérez-Pampin E, Conesa-Zamora P, Swierkot J, den Broeder A, de Vita S, Brix Petersen E, Li Y, Coenen M, Bogunia-Kubik K, Andersen V, Fonseca J, Lund Hetland M, López Nevot M, López-Medina C, Reyes-Zurita F, Netea M, Escudero A, Cáliz R, Collantes-Estévez E, Sánchez-Maldonado J, Sainz J
Kalinke Lab
Immunology
Towards the molecular mechanism of HBV vaccination non-responsiveness
The project will investigate the immunological and genetic causes of vaccination failure in 5% of HBV-vaccinated individuals in order to develop new strategies to improve vaccination protection.
Pessler Lab
Immunology
Predictive biomarkers for a poor immune response to influenza vaccination in elderly individuals
Older people are at high risk of a poor immune response to the flu vaccine. Together with partners, we are looking for biomarkers and risk factors for this inadequate response and are investigating ways to improve the vaccination response.
Pietschmann Lab
Virology
Host and viral factors that govern susceptibility to HCV and RSV
We are investigating why HCV infections sometimes heal spontaneously, but often become chronic, and why RSV infections are severe in some children. We use modern sequencing technologies to analyze the genetic characteristics of hosts and pathogens in order to understand susceptibility.
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Seminar
TWINCORE Seminar
Dr. Verena Krähling
Institute of Virology
Medical Faculty
Marburg University
"Development of vaccine candidates against highly pathogenic viruses"
Seminar
TWINCORE Seminar
Prof. Dr. Andrea Maisner
Institute of Virology
Medical Faculty
Marburg University
"Unconventional plasma membrane clusters as assembly platforms for highly pathogenic Nipah virus: An imaging study"
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
