AI in Research and Administration
TWINCORE establishes task force
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Science Immunology11 (118) : eadw7077
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M, Bender A, Vöcking L, Richter M, Hageb A, Suerdieck V, Arenas Cerro F, Braster Q, Guzman M, Sintes J, Sharma S, Lemnitzer P, Tulotta C, Börgeling Y, Herrero-Cervera A, Flueter H, Reinartz Groba S, Ahern D, Osei-Sarpong C, Zimmer R, Alonso-Gonzalez N, Ortega E, Lienenklaus S, Kalinke U, Ludwig S, Engel D, Rosenbauer F, Monaco C, Dersch P, Kibler A, Cerutti A, Chavakis T, Benedito R, Hidalgo A, Jablonska J, Palomino-Segura M, Soehnlein O
2026Cell Genomics : 101218
Interferon-related inflammaging links epigenetic age acceleration to multimorbidity
Liu Z, Ziogas A, Zhang Y, Gupta M, Föhse K, Taks E, Dulfer E, Sarlea A, Ventriglia L, Geckin B, Ballan M, van Unen N, Helder L, Trittel S, Riese P, Moorlag S, de Bree C, Koeken V, Mourits V, Jaeger M, Pessler F, Guzmán C, Joosten L, Li Y, Xu C, Netea M
2026Gut : gutjnl-2025-337640
CD16+ γδ T cells mediate antibody-dependent cellular cytotoxicity and associate with viral control in chronic hepatitis B virus infection
Schröter P, Steppich K, Fernández Carrera L, Song Z, Klein S, Souleiman R, Urbanek-Quaing M, Lietzau A, Schnieders A, Freyer E, Bremer B, León-Lara X, Almeida V, Gutierrez Jauregui R, Von Kaisenberg C, Bruhn M, Meineke C, Kalinke U, Wedemeyer H, Prinz I, Ravens S, Carpentier A, Bartsch Y, Kraft A, Cornberg M
Bartsch Lab
Immunology
Protective anti-viral immunity – learning from natural examples
In this project, antibodies that help to ward off infections are being investigated in more detail. The aim is to find characteristics that have a protective effect against certain pathogens by comparing different antibody profiles in infections and vaccinations.
Pessler Lab
Immunology
Functional Biomarkers for respiratory infections
This project focuses on lung infections such as influenza, COVID-19, pneumonia and tuberculosis in order to improve diagnostics, patient stratification and therapy. RNA molecules and metabolites are being investigated as biomarkers and complementary therapies.
Pietschmann Lab
Virology
Principles of HCV assembly and entry and their role in virus persistence
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Galardini Lab
Bacteriology
Genotype to phenotype studies in bacteria
By applying statistical genetics methods to pathogen genome sequences, we aim to identify and validate genetic determinants of phenotypes such as pathogenicity, virulence and antibiotic resistance, e.g. in E. coli and P. aeruginosa.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Lecture Series - Regulatory Science and Translational Research - Part 1
"Why is knowledge in regulatory science important for translational medicine and basic science?"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
