Future Day 2026 at TWINCORE
Eleven pupils gain an insight into infection research
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Science Advances12 (19) : eaeb5967
The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis
Ruwisch J, Cazes A, Leiber L, Borie R, Neubert L, Christian L, Thomas de Montpréville V, Szmul A, Moussa F, Verleden S, Gaedcke S, Hegermann J, Fuge J, Ballmaier M, Kamp J, Greer M, Braubach P, Werlein C, Ius F, Graalmann T, Aburahma K, De Sadeleer L, Egashira R, Ackermann M, Yamada D, Hoeper M, Falk C, Gottlieb J, Schiller H, Vanaudenaerde B, Seeliger B, Debray M, Bernaudin J, Knudsen L, Bergot E, Jacob J, Mal H, Jonigk D, Dettmer S, Mordant P, Prasse A, Fadel E, Wuyts W, Crestani B, Kaminski N, Justet A, Schupp J
2026Journal of Virology : e0034226
Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
Hahlin E, Danskog K, Nord S, Becker M, Willekens S, Wibom C, Tanner H, Frängsmyr L, Öhlund D, Sandblad L, Lenman A, Arnberg N
2026Frontiers in Immunology17 : 1734093
Particularly strong immune response to influenza vaccination in patients with decompensated liver cirrhosis linked to systemic inflammation
Heisig J, Ohlendorf V, Nguyen N, Riese P, Trittel S, Zhou L, Alaswad A, Wedemeyer H, Kraft A, Li Y, Cornberg M, Guzmán C, Maasoumy B
Graalmann Lab
Immunology
Cell-selective targeting of immune cells
Immunomodulatory drugs can have systemic side effects. This project is testing nanocarriers that deliver drugs specifically into myeloid immune cells in order to reduce side effects and increase the local effect.
Kalinke Lab
Immunology
Virus control within the CNS
The project investigates the immune response of the central nervous system in viral infections, in particular the role of type I IFN, microglia and monocytes in the development of encephalitis and their influence on seizures and hippocampal damage.
Pietschmann Lab
Virology
Principles of HCV assembly and entry and their role in virus persistence
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Seminar
TWINCORE Seminar
Dr. Verena Krähling
Institute of Virology
Medical Faculty
Marburg University
"Development of vaccine candidates against highly pathogenic viruses"
Seminar
TWINCORE Seminar
Prof. Dr. Andrea Maisner
Institute of Virology
Medical Faculty
Marburg University
"Unconventional plasma membrane clusters as assembly platforms for highly pathogenic Nipah virus: An imaging study"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
