Future Day 2026 at TWINCORE
Eleven pupils gain an insight into infection research
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Lower Saxony International Summer Academy 2026
The LISA Summer School 2026 takes place from 23 August to 11 September 2026. Registration is open until 31 March.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2026Science Immunology11 (118) : eadw7077
Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
Silvestre-Roig C, Chevre R, Farjia M, Bender A, Vöcking L, Richter M, Hageb A, Suerdieck V, Arenas Cerro F, Braster Q, Guzman M, Sintes J, Sharma S, Lemnitzer P, Tulotta C, Börgeling Y, Herrero-Cervera A, Flueter H, Reinartz Groba S, Ahern D, Osei-Sarpong C, Zimmer R, Alonso-Gonzalez N, Ortega E, Lienenklaus S, Kalinke U, Ludwig S, Engel D, Rosenbauer F, Monaco C, Dersch P, Kibler A, Cerutti A, Chavakis T, Benedito R, Hidalgo A, Jablonska J, Palomino-Segura M, Soehnlein O
2026Cell Genomics : 101218
Interferon-related inflammaging links epigenetic age acceleration to multimorbidity
Liu Z, Ziogas A, Zhang Y, Gupta M, Föhse K, Taks E, Dulfer E, Sarlea A, Ventriglia L, Geckin B, Ballan M, van Unen N, Helder L, Trittel S, Riese P, Moorlag S, de Bree C, Koeken V, Mourits V, Jaeger M, Pessler F, Guzmán C, Joosten L, Li Y, Xu C, Netea M
2026Gut : gutjnl-2025-337640
CD16+ γδ T cells mediate antibody-dependent cellular cytotoxicity and associate with viral control in chronic hepatitis B virus infection
Schröter P, Steppich K, Fernández Carrera L, Song Z, Klein S, Souleiman R, Urbanek-Quaing M, Lietzau A, Schnieders A, Freyer E, Bremer B, León-Lara X, Almeida V, Gutierrez Jauregui R, Von Kaisenberg C, Bruhn M, Meineke C, Kalinke U, Wedemeyer H, Prinz I, Ravens S, Carpentier A, Bartsch Y, Kraft A, Cornberg M
Kalinke Lab
Immunology
Towards the molecular mechanism of HBV vaccination non-responsiveness
The project will investigate the immunological and genetic causes of vaccination failure in 5% of HBV-vaccinated individuals in order to develop new strategies to improve vaccination protection.
Pietschmann Lab
Virology
Determinants of protective immunity in HCV: A gold standard for vaccine development
We are investigating how antibodies protect against HCV infection, in particular what properties they have during a healing infection. The aim is to identify antibodies that are important for an effective vaccine against HCV.
Pietschmann Lab
Virology
Host and viral factors that govern susceptibility to HCV and RSV
We are investigating why HCV infections sometimes heal spontaneously, but often become chronic, and why RSV infections are severe in some children. We use modern sequencing technologies to analyze the genetic characteristics of hosts and pathogens in order to understand susceptibility.
Lauber Lab
Virology
Genetic determinants of severe RSV infection in infants
We are investigating how genetic variants influence the risk of severe RSV infections in infants. Exome sequencing and bioinformatic analyses are used to identify causal variants in immunity genes.
Lecture Series - Regulatory Science and Translational Research - Part 5
"Interaction with regulators, e.g. in preparation of a first clinical study"
Lecture Series - Regulatory Science and Translational Research - Part 6
"Challenge Orphan medicines – learnings from the past"
Lecture Series - Regulatory Science and Translational Research - Part 1
"Why is knowledge in regulatory science important for translational medicine and basic science?"
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
