
TWINCORE on the cover
Matthias Bruhn wins the eBioMedicine cover competition.
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Matthias Bruhn wins the eBioMedicine cover competition.
Researchers at TWINCORE and MHH investigate the cause of lung damage in autoimmune diseases
TWINCORE researchers show how viruses escape the immune defence system
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
Bartsch Y, Webb N, Burgess E, Kang J, Lauffenburger D, Julg B
Haller R, Cai Y, DeBuhr N, Rieder J, Schlüter D, Baier C, Rohde H, von Köckritz-Blickwede M, Vital M, Winstel V
Chou Y, Cornberg M
Immunomodulatory drugs for rheumatic diseases specifically influence immune cells and messenger substances. This project investigates their effect on immune responses in order to find individually suitable therapies.
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Studies in the cell culture model show that only a few disinfectants are effective against HEV, which provides important information on hygiene measures for HEV infections. We are also working together to test vaccines for pigs as HEV reservoirs.
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.