Successful start for HCV vaccine project
923,000 € funding for the V³ECTORY project from IBT Lower Saxony
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2025Mabs17 (1) : 2465391
Combinatorial Fc modifications for complementary antibody functionality
Bartsch Y, Webb N, Burgess E, Kang J, Lauffenburger D, Julg B
2025Emerging Microbes & Infections : 2482709
Transmissible Staphylococcus pseudintermedius thwarts neutrophil extracellular trap-driven containment to promote invasive disease
Haller R, Cai Y, DeBuhr N, Rieder J, Schlüter D, Baier C, Rohde H, von Köckritz-Blickwede M, Vital M, Winstel V
2025Hepatology (baltimore, Md.) : 10.1097/HEP.0000000000001340
Reply: Refining epigenetic insights in HBV-Specific T Cell restoration
Chou Y, Cornberg M
Kalinke Lab
Immunology
Immunological sensing of cytomegalovirus (CMV)
The project investigates how HCMV is recognized by the immune system and which mechanisms the virus uses to camouflage itself. The aim is to understand the immune reactions and develop therapies for severely affected patients.
Kalinke Lab
Immunology
Cell-selective delivery of active compounds
The project is developing methods to specifically transport antibiotics into cells such as alveolar macrophages, which are important in Mycobacterium tuberculosis infections. The aim is to overcome resistance and reduce side effects.
Pietschmann Lab
Virology
Host and viral factors that govern susceptibility to HCV and RSV
We are investigating why HCV infections sometimes heal spontaneously, but often become chronic, and why RSV infections are severe in some children. We use modern sequencing technologies to analyze the genetic characteristics of hosts and pathogens in order to understand susceptibility.
Lauber Lab
Virology
Pandemic preparedness: assessing spill-over risk of RNA viruses
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
