2026Journal of Virology : e0111726
Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells
Xie E, Schubert M, Reeb J, Seligmann B, Schaks M, Müsken M, Steffen A, Stradal T, Haid S, Rottner K, Sieben C
Dr. Sibylle Haid
Teamleader Respiratory Viruses
About
Sibylle Haid is deputy head of institute and senior postdoc at the Institute for Experimental Virology at TWINCORE. She studied molecular medicine at the University of Freiburg and graduated in 2006. She completed her doctorate at the Hannover Medical School (Institute for Experimental Virology) on her work on the cell entry mechanism of the hepatitis C virus. Since 2012, she has been focusing her work on respiratory infections, with a particular emphasis on respiratory syncytial virus (RSV). She is working on the genetic determinants that cause severe RSV infection and on the development of new antiviral drugs.
Research Lab
Publications
2026Science Advances12 (25) : eaed4499
Respiratory syncytial viral load drives ciliated cell dedifferentiation and suppresses antiviral immunity
Berg K, Haid S, Vafadarnejad E, Carpentier A, Geffers R, Wiegmann B, Saliba A, Erhard F, Pietschmann T
2025Proceedings of the National Academy of Sciences of the United States of America122 (28) : e2500276122
Mycophenolic acid treatment drives the emergence of novel SARS-CoV-2 variants
Meister T, Nocke M, Heinen N, Burkard T, Brüggemann Y, Westhoven S, Trüeb B, Ebert N, Thomann L, Lubieniecki K, Lubieniecka J, Döring K, Herrmann M, Haid S, Pietschmann T, Wiegmann B, Tao R, Pfefferle S, Addo M, Thiel V, Drexler I, Babel N, Phuc Nguyen H, Brown R, Todt D, Steinmann E, Pfaender S
2024Frontiers in Immunology15 : 1443665
A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI)
Hartmann C, Khan R, Schöning J, Richter M, Willers M, Pirr S, Heckmann J, Dirks J, Morbach H, Konrad M, Fries E, Winkler M, Büchel J, Seidenspinner S, Fischer J, Vollmuth C, Meinhardt M, Marissen J, Schmolke M, Haid S, Pietschmann T, Backes S, Dölken L, Löber U, Keil T, Heuschmann P, Wöckel A, Sagar, Ulas T, Forslund-Startceva S, Härtel C, Viemann D
2024Antimicrobial Agents and Chemotherapy68 (3) : e0121023
Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets
Haid S, Matthaei A, Winkler M, Sake S, Gunesch A, Milke V, Köhler N, Rückert J, Vieyres G, Kühl D, Nguyen T, Göhl M, Lasswitz L, Zapatero-Belinchón F, Brogden G, Gerold G, Wiegmann B, Bilitewski U, Brown R, Brönstrup M, Schulz T, Pietschmann T
Posts
How RSV manipulates the immune response in respiratory cells
TWINCORE researchers investigate gene activity in host cells
New hope in the fight against RSV
TWINCORE researchers discover promising drug candidate
Bacterial weapons against viral diseases
Discovery of two novel classes of natural products with activity against RNA viruses