Immunology

Graalmann Lab

Theresa Graalmann
Head

Dr. Dr. Theresa Graalmann

Publications


2025Arthritis & rheumatology (Hoboken, N.J.)77 (1) : 59-66

Toll-Like Receptor 8 is Expressed in Monocytes in Contrast to Plasmacytoid Dendritic Cells and Mediates Aberrant Interleukin-10 Responses in Patients With Systemic Sclerosis

Ehlers C, Thiele T, Biermann H, Traidl S, Bruns L, Ziegler A, Schefzyk M, Bartsch L, Kalinke U, Witte T, Graalmann T

2024The Journal of allergy and clinical immunology154 (4) : 1069-1075

Phenotypic and pathomechanistic overlap between tapasin and TAP deficiencies

Elsayed A, von Hardenberg S, Atschekzei F, Graalmann T, Jänke C, Witte T, Ringshausen F, Sogkas G

2024Frontiers in immunology15 : 1400348

JAK inhibitors to treat STAT3 gain-of-function: a single-center report and literature review

Atschekzei F, Traidl S, Carlens J, Schütz K, von Hardenberg S, Elsayed A, Ernst D, Risser L, Thiele T, Graalmann T, Raab J, Baumann U, Witte T, Sogkas G

2024European journal of immunology54 (7) : e2451056

Diversification of the VH3-53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS-CoV-2 virus variants

Bruhn M, Obara M, Salam A, Costa B, Ziegler A, Waltl I, Pavlou A, Hoffmann M, Graalmann T, Pöhlmann S, Schambach A, Kalinke U

2024The Journal of infection88 (1) : 57-60

Memory B cells anticipate SARS-CoV-2 variants through somatic hypermutation

Bruhn M, Obara M, Chiyyeadu A, Costa B, Salam A, Ziegler A, Waltl I, Pavlou A, Bonifacius A, Hoffmann M, Graalmann T, Pöhlmann S, Eiz-Vesper B, Schambach A, Kalinke U

2024The Lancet. Infectious diseases24 (1) : e1-e3

Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination

Stankov M, Hoffmann M, Gutierrez Jauregui R, Cossmann A, Morillas Ramos G, Graalmann T, Winter E, Friedrichsen M, Ravens I, Ilievska T, Ristenpart J, Schimrock A, Willenzon S, Ahrenstorf G, Witte T, Förster R, Kempf A, Pöhlmann S, Hammerschmidt S, Dopfer-Jablonka A, Behrens G

2023RMD open9 (4) : e003507

Rituximab to treat prolidase deficiency due to a novel pathogenic copy number variation in PEPD

Atschekzei F, Fedchenko M, Elsayed A, Dubrowinskaja N, Graalmann T, Ringshausen F, Witte T, Sogkas G

2021Annals of the rheumatic diseases80 (12) : 1537-1544

B cell depletion impairs vaccination-induced CD8+ T cell responses in a type I interferon-dependent manner

Graalmann T, Borst K, Manchanda H, Vaas L, Bruhn M, Graalmann L, Koster M, Verboom M, Hallensleben M, Guzmán C, Sutter G, Schmidt R, Witte T, Kalinke U

2021Frontiers in immunology12 : 721738

Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy

Bošnjak B, Odak I, Ritter C, Stahl K, Graalmann T, Steinbrück L, Blasczyk R, Falk C, Schulz T, Wedemeyer H, Cornberg M, Ganser A, Förster R, Koenecke C

2021Journal of controlled release : official journal of the Controlled Release Society334 : 201-212

Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells

Durán V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro J, Costa B, Koller N, Lueder Y, Wiegmann B, Brandes G, Kaever V, Lehr C, Lepenies B, Tampé R, Förster R, Bošnjak B, Furch M, Graalmann T, Kalinke U


Posts

New junior research group "Translational Immunology

Clinician scientist Theresa Graalmann starts her own group at TWINCORE

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Christine Ehlers and Theresa Graalmann in the lab

New approaches to research into systemic sclerosis 

A research team at TWINCORE was able to establish that TLR8 influences the formation of disease-relevant cytokines.

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The scientist Dr Matt Matthias Bruhn is sitting at a sterile bench in the laboratory.

Diversity is the key

How B cells recognise new variants of SARS-CoV-2

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Vaccination success without B cells

Communication between immune cells determines response to vaccination

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A Trojan horse against tuberculosis

New transport route for antibiotics directly into infected cells

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TWINCORE scientists identified cause of susceptibility to infection in rheumatism patients

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6 November 2014 Magic cap lifted - TWINCORE scientists decode a new camouflage mechanism of cytomegalovirus

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6 August 2014 Where does the interferon for the early virus defence come from?

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28 September 10 Neuer Mechanismus bei der Virenabwehr entdeckt: Interferon macht das spezifische Immunsystem gegen Viren mobil

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