New approaches to research into systemic sclerosis
A research team at TWINCORE was able to establish that TLR8 influences the formation of disease-relevant cytokines.
Immunology
Graalmann Lab
Projects
Graalmann Lab
Immunology
Tissue inflammation upon chronic rheumatic diseases
Patients with chronic rheumatic diseases have an increased risk of infection due to severe inflammation. This project investigates inflammation in various tissues, particularly in systemic sclerosis, in order to develop targeted therapies.
Graalmann Lab
Immunology
Indirect effects of immunomodulatory drugs
Immunomodulatory drugs for rheumatic diseases specifically influence immune cells and messenger substances. This project investigates their effect on immune responses in order to find individually suitable therapies.
Graalmann Lab
Immunology
Cell-selective targeting of immune cells
Immunomodulatory drugs can have systemic side effects. This project is testing nanocarriers that deliver drugs specifically into myeloid immune cells in order to reduce side effects and increase the local effect.
Posts
Diversity is the key
How B cells recognise new variants of SARS-CoV-2
Vaccination success without B cells
Communication between immune cells determines response to vaccination
A Trojan horse against tuberculosis
New transport route for antibiotics directly into infected cells
TWINCORE scientists identified cause of susceptibility to infection in rheumatism patients
Magic cap lifted
TWINCORE scientists decode a new camouflage mechanism of cytomegalovirus
Where does the interferon for the early virus defence come from?
28 September 10 Neuer Mechanismus bei der Virenabwehr entdeckt: Interferon macht das spezifische Immunsystem gegen Viren mobil
New junior research group "Translational Immunology
Clinician scientist Theresa Graalmann starts her own group at TWINCORE
