Hard to break down
Hepatitis E virus defies alcohol-based hand disinfectants.Joint press release by TWINCORE, Hannover Medical School and Ruhr University Bochum
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Behrendt Lab
Projects
Behrendt Lab
Virology
Antiviral Strategies Against HEV
Together with the Department of Structural Biology at the University of Lübeck, human, strongly neutralizing antibodies against HEV were identified and characterized for the first time. These showed a protective effect in the mouse model and are currently being further developed for clinical application, including mRNA-based application methods.
Behrendt Lab
Virology
Determinants of the Clinical Course of Infection
Human, potentially neutralizing antibodies against HEV have advanced the development of new detection methods for the virus in patient samples. Serological and functional analyses are used to determine markers for the course and treatment of chronic infections.
Behrendt Lab
Virology
Prevention of HEV Infection
Studies in the cell culture model show that only a few disinfectants are effective against HEV, which provides important information on hygiene measures for HEV infections. We are also working together to test vaccines for pigs as HEV reservoirs.
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A precise measure of protective immunity
New tool aims to make HCV vaccine search easier
Read moreFirst robust cell culture model for the hepatitis E virus
A mutation switches the turbo on during virus replication. This is a blessing for research.
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