Arnaud Carpentier

Dr. Arnaud Carpentier

Postdoctoral Researcher

About

Arnaud Carpentier is a postdoctoral researcher at the Institute for Experimental Virology at TWINCORE. He studied biology in Lille and Paris (France) and graduated in 2009. He obtained his PhD at the Pierre and Marie Curie University (Paris) and worked on hepatitis C infection of primary human hepatocytes. 

In 2010, he joined the Liver Disease Group of Dr T. Jake Liang at the National Institute of Health (NIH, Bethesda, USA) as a postdoctoral fellow. There, he focused on the development of new relevant in vitro and in vivo models for hepatitis B virus (HBV) and hepatitis C virus (HCV) infections using hepatocytes derived from human pluripotent stem cells (also known as HLCs). 

In 2015, he joined the Institute for Experimental Virology at TWINCORE, where he investigated the innate immune response to HCV infection in HLCs. He now focuses his work on studying the interactions between hepatitis D virus and its host pathogens mainly using HLCs and single-cell RNA sequencing.


Publications

2024Nature Communications15 (1) : 1173

Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

Sake S, Zhang X, Rajak M, Urbanek-Quaing M, Carpentier A, Gunesch A, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee A, Johnson K, Morwood K, Rox K, Elgaher W, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët J, Rameix-Welti M, Hirsch A, Herold E, Empting M, Lauber C, Schulz T, Krey T, Haid S, Pietschmann T

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