Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis
Mulenge F, Gern O, Busker L, Aringo A, Ghita L, Waltl I, Pavlou A, Kalinke U
Dr. Andreas Pavlou is postdoctoral researcher in the Institute for Experimental Infection Research at TWINCORE. Upon finalizing his BSc and MSc degree studies on Molecular Biology & Genetics and Molecular Medicine (Neurobiology) in Alexandroupoli and Athens, respectively, he completed his doctorate in 2021 at the University of Veterinary Medicine Hannover and the Hannover Medical School under the supervision of Prof. Dr. med. Martin Stangel. There, he investigated the role of glial cells such as microglia and astrocytes during viral encephalitis in mice. Nowadays, his research focuses on responses of myeloid cells in the virus infected CNS and lung. A key question is how myeloid cells communicate with cells of the adaptive immune response upon infection with a variety of viruses, including vesicular stomatitis virus, mouse adapted SARS-CoV-2 as well as mouse cytomegalovirus, herpes simplex virus type I, and tick-borne encephalitis virus.
Mulenge F, Gern O, Busker L, Aringo A, Ghita L, Waltl I, Pavlou A, Kalinke U
Pavlou A, Mulenge F, Gern O, Busker L, Greimel E, Waltl I, Kalinke U
Bruhn M, Obara M, Chiyyeadu A, Costa B, Salam A, Ziegler A, Waltl I, Pavlou A, Bonifacius A, Hoffmann M, Graalmann T, Pöhlmann S, Eiz-Vesper B, Schambach A, Kalinke U