Pseudovirus-based analysis of host cell entry and vaccine-induced neutralisation of Bundibugyo virus
Hoffmann M, Shandheep A, Pavlou A, Rahmel-Stein K, Ly M, Chen N, Moor N, Moldenhauer A, Drosten C, Kalinke U, Addo M, Pöhlmann S

Dr. Andreas Pavlou is postdoctoral researcher in the Institute for Experimental Infection Research at TWINCORE. Upon finalizing his BSc and MSc degree studies on Molecular Biology & Genetics and Molecular Medicine (Neurobiology) in Alexandroupoli and Athens, respectively, he completed his doctorate in 2021 at the University of Veterinary Medicine Hannover and the Hannover Medical School under the supervision of Prof. Dr. med. Martin Stangel. There, he investigated the role of glial cells such as microglia and astrocytes during viral encephalitis in mice. Nowadays, his research focuses on responses of myeloid cells in the virus infected CNS and lung. A key question is how myeloid cells communicate with cells of the adaptive immune response upon infection with a variety of viruses, including vesicular stomatitis virus, mouse adapted SARS-CoV-2 as well as mouse cytomegalovirus, herpes simplex virus type I, and tick-borne encephalitis virus.
Hoffmann M, Shandheep A, Pavlou A, Rahmel-Stein K, Ly M, Chen N, Moor N, Moldenhauer A, Drosten C, Kalinke U, Addo M, Pöhlmann S
Pavlou A, Ghita L, Mulenge F, Waltl I, Gern O, Larsen P, Costa B, Duran V, Busker L, Robertson S, Lueder Y, Halle S, Förster R, Best S, Stangel M, Kalinke U
Heydemann L, Ciurkiewicz M, Störk T, Zdora I, Hülskötter K, Gregor K, Michaely L, Reineking W, Schreiner T, Beythien G, Volz A, Tuchel T, Meyer Zu Natrup C, Schünemann L, Clever S, Henneck T, von Köckritz-Blickwede M, Schaudien D, Rohn K, Schughart K, Geffers R, Kaneko M, Kato Y, Gross C, Amanakis G, Pavlou A, Baumgärtner W, Armando F
Gern O, Pavlou A, Mulenge F, Busker L, Ghita L, Aringo A, Costa B, Spanier J, Waltl I, Stangel M, Kalinke U
Pavlou A, Mulenge F, Gern O, Busker L, Greimel E, Waltl I, Kalinke U

A team of researchers from Hamburg, Berlin, Göttingen and Hannover has provided evidence of possible cross-protection offered by an already authorised Zaire Ebola virus vaccine.

How immune cells in the brain coordinate their work

Researchers in Hannover have developed a new method for studying neuroinfections.