2013
Entry and replication of recombinant hepatitis C viruses in cell culture
Vieyres G, Pietschmann T
Erschienen in
Methods (san Diego, Calif.): Volume 59, Issue 2, Page 233-48
Abstract
Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus and belongs to the Flaviviridae family. The heavy health burden associated with the virus infection in humans and the intriguing peculiarities of the interaction between the HCV replication cycle and the hepatocyte host cell have stimulated a flourishing research field. The present review aims at recapitulating the different viral and cellular systems modelling HCV entry and replication, and in particular at gathering the tools available to dissect the HCV entry pathway.
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