Season's Greetings
TWINCORE wishes you happy holidays and a successful new year
Infection research at the interface between clinical practice and basic research
TWINCORE was founded in 2008 by the Helmholtz Centre for Infection Research and the Hannover Medical School. We combine the expertise of medical professionals and scientists from a wide range of disciplines to find answers to the pressing questions in infection research. Our focus: translational research – the bridge between basic science and clinical application.
Research
We conduct translational infection research to improve the prevention, diagnosis and treatment of infectious diseases in humans. We focus on three areas that characterize our research work. Find out here how we proceed and what results we achieve.
Labs at TWINCORE
Under the leadership of our best scientists, various labs are working on different projects within our research topics.
2025The Journal of Infectious Diseases : jiaf654
Transient interferon-driven NK cell activation in acute hepatitis C
Strunz B, Zhan Q, Khera T, Hengst J, Jankovic M, Deterding K, Niehrs A, Cornberg M, Xu C, Wedemeyer H, Björkström N
2025Plos One20 (12) : e0337890
Dynamic growth risk of incidentally detected gallbladder polyps-A retrospective, single-center analysis
Heinrich S, Ten Thoren P, Behrendt P, Hagenah J, Wedemeyer H, Potthoff A, Maasoumy B
2025Journal of Autoimmunity158 : 103517
Humoral correlates of clinical response to thymectomy in myasthenia gravis
Sousa C, Terroba-Navajas P, Tzartos J, Orešković I, Pučić-Baković M, Lauc G, Bartsch Y, Kaminski H, Lünemann J
Kalinke Lab
Immunology
Cell-selective delivery of active compounds
The project is developing methods to specifically transport antibiotics into cells such as alveolar macrophages, which are important in Mycobacterium tuberculosis infections. The aim is to overcome resistance and reduce side effects.
Pietschmann Lab
Virology
Principles of HCV assembly and entry and their role in virus persistence
We are investigating how the association of HCV with lipoproteins contributes to the persistence of the virus by influencing entry into liver cells and protecting against antibodies. The aim is to gain new insights for the development of an HCV vaccine.
Galardini Lab
Bacteriology
Genotype to phenotype studies in bacteria
By applying statistical genetics methods to pathogen genome sequences, we aim to identify and validate genetic determinants of phenotypes such as pathogenicity, virulence and antibiotic resistance, e.g. in E. coli and P. aeruginosa.
Lauber Lab
Virology
Genetic determinants of severe RSV infection in infants
We are investigating how genetic variants influence the risk of severe RSV infections in infants. Exome sequencing and bioinformatic analyses are used to identify causal variants in immunity genes.
There are currently no events.
Career at TWINCORE
Want to become part of TWINCORE?
Take a look at our job advertisements to see if there is something suitable for you or send us an unsolicited application.
