Dr. Sibylle Haid

Teamleader Respiratory Viruses

About

Sibylle Haid is deputy head of institute and senior postdoc at the Institute for Experimental Virology at TWINCORE. She studied molecular medicine at the University of Freiburg and graduated in 2006. She completed her doctorate at the Hannover Medical School (Institute for Experimental Virology) on her work on the cell entry mechanism of the hepatitis C virus. Since 2012, she has been focusing her work on respiratory infections, with a particular emphasis on respiratory syncytial virus (RSV). She is working on the genetic determinants that cause severe RSV infection and on the development of new antiviral drugs.


Publications

2024Antimicrobial agents and chemotherapy68 (3) : e0121023

Repurposing screen identifies novel candidates for broad-spectrum coronavirus antivirals and druggable host targets

Haid S, Matthaei A, Winkler M, Sake S, Gunesch A, Milke V, Köhler N, Rückert J, Vieyres G, Kühl D, Nguyen T, Göhl M, Lasswitz L, Zapatero-Belinchón F, Brogden G, Gerold G, Wiegmann B, Bilitewski U, Brown R, Brönstrup M, Schulz T, Pietschmann T

2024Nature communications15 (1) : 1173

Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

Sake S, Zhang X, Rajak M, Urbanek-Quaing M, Carpentier A, Gunesch A, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee A, Johnson K, Morwood K, Rox K, Elgaher W, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët J, Rameix-Welti M, Hirsch A, Herold E, Empting M, Lauber C, Schulz T, Krey T, Haid S, Pietschmann T

2023The Journal of hospital infection141 : 25-32

Virucidal activity of oral, hand, and surface disinfectants against respiratory syncytial virus

Meister T, Friesland M, Frericks N, Wetzke M, Haid S, Steinmann J, Todt D, Pietschmann T, Steinmann E

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Posts

5 July 2013 Specific characteristics of hepatitis C virus - a first step towards individualized HCV therapy

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Microscopic image of cells transfected with RSV. Green: RSV-F protein labelled with GFP in the cytoplasm of the cells, magenta: RSV-F protein, blue: cell nuclei. ©TWINCORE/Carpentier

New hope in the fight against RSV

TWINCORE researchers discover promising drug candidate 

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Lung cell infected with SARS-CoV-2 forms new virus particles (green) in its cytoplasm (violet: cell nuclei). ©HZI/Ulfert Rand

Bacterial weapons against viral diseases

Discovery of two novel classes of natural products with activity against RNA viruses 

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