Dr. Julie Sheldon

Teamleitung Hepatitis-Viren

About

Julie Sheldon works as a postdoc at the Institute for Experimental Virology at TWINCORE. She studied microbiology at the University of Liverpool (1991-1994) and completed her master's degree in the group of Thomas Schulz at the Hannover Medical School (MHH) in 2002. After completing her doctorate in Madrid in 2008, she received several research grants and worked, among others, in the group of Prof. Charles Rice in New York and Prof. Esteban Domingo in Madrid. In 2013, Julie moved to Hannover to work in the group of Professor Thomas Pietschmann, where she is investigating the tropism of the hepatitis C virus.


Publications

2024Journal of virology98 (3) : e0192123

Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes

Frericks N, Brown R, Reinecke B, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran F, Steinmann E, Pietschmann T, Sheldon J

2023bioRxiv : the preprint server for biology : 2023.11.22.568224

Hepatitis C virus cell culture adaptive mutations enhance cell culture propagation by multiple mechanisms but boost antiviral responses in primary human hepatocytes

Frericks N, Brown R, Reinecke B, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran F, Steinmann E, Pietschmann T, Sheldon J

2023Microbiology spectrum11 (4) : e0128423

Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses

Zhang Y, Kinast V, Sheldon J, Frericks N, Todt D, Zimmer M, Caliskan N, Brown R, Steinmann E, Pietschmann T

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Posts

TWINCORE researcher Dr. Julie Sheldon in the laboratory next to a digital microscope

A major step for HCV research

Research team from Hannover adapts hepatitis C virus to infect mouse liver cells

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Two murine restriction factors limiting hepatitis C infection described

Research team at TWINCORE, with international collaborators, clarifies why mice are not susceptible to infection with hepatitis C virus 

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