Publications

2021Gut70 (9) : 1734-1745

Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies

Bankwitz D, Bahai A, Labuhn M, Doepke M, Ginkel C, Khera T, Todt D, Ströh L, Dold L, Klein F, Klawonn F, Krey T, Behrendt P, Cornberg M, McHardy A, Pietschmann T

2021Journal of virology95 (10) : e00245-21

Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements

Tegtmeyer B, Vieyres G, Todt D, Lauber C, Ginkel C, Engelmann M, Herrmann M, Pfaller C, Vondran F, Broering R, Vafadarnejad E, Saliba A, Puff C, Baumgärtner W, Miskey C, Ivics Z, Steinmann E, Pietschmann T, Brown R

2020Science advances6 (45) : eabd3233

Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

Brown R, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran F, Krey T, Ströh L, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr A, McClure C, Randall G, Baktash Y, Ploss A, Thi V, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice C, Pietschmann T

2020Medical microbiology and immunology209 (4) : 499-514

Single-nucleotide variants in human CD81 influence hepatitis C virus infection of hepatoma cells

Alberione M, Moeller R, Kirui J, Ginkel C, Doepke M, Ströh L, Machtens J, Pietschmann T, Gerold G

2014Hepatology (Baltimore, Md.)60 (2) : 508-20

Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles

Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Behrendt P, Brown R, Ciesek S, Wedemeyer H, Sarrazin C, Kaderali L, Pietschmann T, Steinmann E

2014Hepatology (Baltimore, Md.)59 (1) : 78-88

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells

Frentzen A, Anggakusuma, Gürlevik E, Hueging K, Knocke S, Ginkel C, Brown R, Heim M, Dill M, Kröger A, Kalinke U, Kaderali L, Kuehnel F, Pietschmann T

2014Journal of virology88 (1) : 667-78

Analysis of serine codon conservation reveals diverse phenotypic constraints on hepatitis C virus glycoprotein evolution

Brown R, Koutsoudakis G, Urbanowicz R, Mirza D, Ginkel C, Riebesehl N, Calland N, Albecka A, Price L, Hudson N, Descamps V, Backx M, McClure C, Duverlie G, Pecheur E, Dubuisson J, Perez-del-Pulgar S, Forns X, Steinmann E, Tarr A, Pietschmann T, Ball J

2013Journal of virology87 (24) : 13297-306

Characterization of hepatitis C virus intra- and intergenotypic chimeras reveals a role of the glycoproteins in virus envelopment

Steinmann E, Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Hillung J, Gentzsch J, Lauber C, Brown R, Frentzen A, Pietschmann T