Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses
Siddharta A, Pfaender S, Vielle N, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch M, Brill F, Steinmann J, Steinmann J, Becker S, Alves M, Pietschmann T, Eickmann M, Thiel V, Steinmann E
Published in
The Journal of infectious diseases: Volume 215, Issue 6, Page 902-906
Abstract
The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.
Open in PubMedAuthors
Martina Friesland
Technische Assistentin
Prof. Thomas Pietschmann
Institutsleiter