Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions

M Martin-Fernandez, Maria Bravo Garcia-Morato, Conor Gruber, Sara Murias Loza, Muhammad Nasir Hayat Malik, Fahad Alsohime, Abdullah Alakeel, Rita Valdez, Sofija Buta, Guadalupe Buda, Marcelo A. Marti, Margarita Larralde, Bertrand Boisson, Marta Feito Rodriguez, Xueer Qiu, Maya Chrabieh, Mohammed Al Ayed, Saleh Al Muhsen, Jigar V. Desai, Elise M.N. Ferre, Sergio D. Rosenzweig, Blanca Amador-Borrero, Luz Yadira Bravo-Gallego, Ruth Olmer, Sylvia Merkert, Montserrat Bret, Amika K. Sood, Abdulkarim Al rabiaah, Mohamad Hani Temsah, Rabih Halwani, Michelle Hernandez, Frank Pessler, Jean-Laurent Casanova, Jacinta Bustamante, Michail S. Lionakis, Dusan Bogunovic