Chris Lauber completed his bioinformatics studies at the University of Jena in 2007. In 2012, he completed his PhD in the group of Alexander Gorbalenya at Leiden University Medical Center, Leiden, Netherlands, on the topic of virus evolution and bioinformatics. Chris received the NBIC Young Investigator award for the best PhD thesis in bioinformatics defended in the Netherlands in 2012. In 2013, he joined the University of Technology Dresden, working in the field of virus discovery and OMICs data analysis. After a short stay as a data scientist at the biotech start-up Lipotype GmbH, he was appointed junior professor (W1) at the Hannover Medical School in June 2020 as part of the RESIST cluster of excellence.
Chris leads the research group “Computational Virology” at TWINCORE. focusing on virus discovery and evolution, virus taxonomy, the role of viromes in health and disease, and susceptibility factors for severe viral infections.
Using high-performance computers, we analyze NGS data to discover unknown viruses in the human and animal virome that could influence disease risks. We investigate the virome as a factor for infections and diseases such as cancer and immunodeficiencies.
The CoViPa consortium uses computer-assisted high-throughput virus discovery and evolutionary analyses to identify RNA viruses with high spillover risk and potential animal host reservoirs and to investigate new pathogenicity factors.
We are investigating how genetic variants influence the risk of severe RSV infections in infants. Exome sequencing and bioinformatic analyses are used to identify causal variants in immunity genes.
Reichert I, Lee J, Weber L, Fuh M, Schlaeger L, Rößler S, Kinast V, Schlienkamp S, Conradi J, Vondran F, Pfaender S, Scaturro P, Steinmann E, Bartenschlager R, Pietschmann T, Heeren J, Lauber C, Vieyres G
Wyler E, Lauber C, Manukyan A, Deter A, Quedenau C, Teixeira Alves L, Wylezich C, Borodina T, Seitz S, Altmüller J, Landthaler M
Sake S, Zhang X, Rajak M, Urbanek-Quaing M, Carpentier A, Gunesch A, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee A, Johnson K, Morwood K, Rox K, Elgaher W, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët J, Rameix-Welti M, Hirsch A, Herold E, Empting M, Lauber C, Schulz T, Krey T, Haid S, Pietschmann T
TWINCORE researchers discover promising drug candidate
Research team at TWINCORE, with international collaborators, clarifies why mice are not susceptible to infection with hepatitis C virus
Group leader Chris Lauber funded by RESIST