2024PLoS Pathog
Deep mining of the Sequence Read Archive reveals major genetic innovations in coronaviruses and other nidoviruses of aquatic vertebrates
C Lauber, X Zhang, J Vaas, F Klingler, P Mutz, A Dubin, T Pietschmann, O Roth, B W Neuman, A E Gorbalenya, R Bartenschlager, S Seitz
2024Transpl Int
In Vitro Profiling of Commonly Used Post-transplant Immunosuppressants Reveals Distinct Impact on Antiviral T-cell Immunity Towards CMV
M B Krueger, A Bonifacius, A C Dragon, M M Santamorena, B Nashan, R Taubert, U Kalinke, B Maecker-Kolhoff, R Blasczyk, B Eiz-Vesper
in pressEur J Immunol
Diversification of the VH3‐53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS‐CoV‐2 virus variants
M Bruhn, M Obara, A Salam, B Costa, A Ziegler, I Waltl, A Pavlou, M Hoffmann, T Graalmann, S Pöhlmann, A Schambach, U Kalinke
2024Sci Rep
MORITS: An improved method to predict peptides from heterologous proteins that are recognized by the same T-cell receptor
M Bruhn, M Spatz, U Kalinke
2024Proc Natl Acad Sci U S A
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa
J Krueger, M Preusse, N Oswaldo Gomez, Y N Frommeyer, S Doberenz, A Lorenz, A Kordes, S Grobe, M Musken, D P Depledge, S L Svensson, S Weiss, V Kaever, A Pich, CM Sharma, Z Ignatova, S Haussler
in pressmBio
Tetramerization is essential for the enzymatic function of the
Pseudomonas aeruginosa
virulence factor UDP-glucose pyrophosphorylase
L Dirr, S Cleeves, I Ramón Roth, L Li, T Fiebig, T Ve, S Häussler, A Braun, M von Itzstein, J I Führing
2024JHEP Rep
Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment
A Gömer, K Dinkelborg, M Klöhn, M Jagst, M H Wißing, N Frericks, P Nörenberg, P Behrendt, M Cornberg, H Wedemeyer, E Steinmann, B Maasoumy, D Todt
2024Nat Commun
Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells
B Costa, J Becker, T Krammer, F Mulenge, V Duran, A Pavlou, O L Gern, X Chu, Y Li, L Cicin-Sain, B Eiz-Vesper, M Messerle, L Dölken, AE Saliba, F Erhard, U Kalinke
2024J Antimicrob Chemother
Identification of a CTX-M-255 β-lactamase containing a G239S substitution selectively conferring resistance to penicillin/β-lactamase inhibitor combinations
M R Andreasen, T Rick, N R Alexandersen, K H Hansen, M S Pedersen, J K Warweitzky, C M Botelho, S Häussler, L Jelsbak, K Schønning
2024J Virol
Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes
N Frericks, R J P Brown, B M Reinecke, M Herrmann, Y Brüggemann, D Todt, C Miskey, F W R Vondran, E Steinmann, T Pietschmann, J Sheldon