2021

Quantitative image analysis of microbial communities with BiofilmQ

Hartmann R, Jeckel H, Jelli E, Singh P, Vaidya S, Bayer M, Rode D, Vidakovic L, Díaz-Pascual F, Fong J, Dragoš A, Lamprecht O, Thöming J, Netter N, Häussler S, Nadell C, Sourjik V, Kovács Á, Yildiz F, Drescher K

Published in

Nature Microbiology: Volume 6, Issue 2, Page 151-156

Abstract

Biofilms are microbial communities that represent a highly abundant form of microbial life on Earth. Inside biofilms, phenotypic and genotypic variations occur in three-dimensional space and time; microscopy and quantitative image analysis are therefore crucial for elucidating their functions. Here, we present BiofilmQ-a comprehensive image cytometry software tool for the automated and high-throughput quantification, analysis and visualization of numerous biofilm-internal and whole-biofilm properties in three-dimensional space and time.

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Cite this publication

DOI: 10.1038/s41564-020-00817-4