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(p)ppGpp imposes graded transcriptional changes to impair motility and promote antibiotic tolerance in biofilms
Engelhardt F, Turnbull K, Gür M, Müsken M, Preusse M, Häussler S, Roghanian M
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The Submucosal Microbiome Correlates with Peri-implantitis Severity
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tRNA hydroxylation is an epitranscriptomic modulator of metabolic states affecting Pseudomonas aeruginosa pathogenicity
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2025Proceedings of the National Academy of Sciences of the United States of America122 (27) : e2415345122
Epigenetic cellular memory in Pseudomonas aeruginosa generates phenotypic variation in response to host environments
Vatareck E, Rick T, Oswaldo Gomez N, Bandyopadhyay A, Kramer J, Strunin D, Erdmann J, Hartmann O, Alpers K, Boedeker C, Steffen A, Sieben C, Zhao G, Tomasch J, Häussler S
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Defining expansions and perturbations to the RNA polymerase III transcriptome and epitranscriptome by modified direct RNA nanopore sequencing
Verstraten R, Cetraro P, Fitzpatrick A, Alwie Y, Frommeyer Y, Loliashvili E, Stein S, Häussler S, Ouwendijk W, Depledge D
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Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells
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Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase
Dirr L, Cleeves S, Ramón Roth I, Li L, Fiebig T, Ve T, Häussler S, Braun A, von Itzstein M, Führing J
2024The Journal of Antimicrobial Chemotherapy79 (4) : 810-814
Identification of a CTX-M-255 β-lactamase containing a G239S substitution selectively conferring resistance to penicillin/β-lactamase inhibitor combinations
Andreasen M, Rick T, Alexandersen N, Hansen K, Pedersen M, Warweitzky J, Botelho C, Häussler S, Jelsbak L, Schønning K
2024Proceedings of the National Academy of Sciences of the United States of America121 (11) : e2312874121
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa
Krueger J, Preusse M, Oswaldo Gomez N, Frommeyer Y, Doberenz S, Lorenz A, Kordes A, Grobe S, Müsken M, Depledge D, Svensson S, Weiss S, Kaever V, Pich A, Sharma C, Ignatova Z, Häussler S