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Publications

2025Ebiomedicine116 : 105770

Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies

Bruhn M, Obara M, Gonzalez-Hernandez M, Reineking W, Salam A, Mirolo M, Hinrichs I, Mergani A, Bartsch Y, Schambach A, Zimmer G, Baumgärtner W, Osterhaus A, Kalinke U

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2025Jhep Reports : Innovation in Hepatology7 (8) : 101429

Single-cell analysis of mature hepatocytes reveals an IRF1-driven restriction of HDV infection

Lange F, Garn J, Bruhn M, Pietschmann T, Carpentier A

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2024European Journal of Immunology54 (7) : e2451056

Diversification of the VH3-53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS-CoV-2 virus variants

Bruhn M, Obara M, Salam A, Costa B, Ziegler A, Waltl I, Pavlou A, Hoffmann M, Graalmann T, Pöhlmann S, Schambach A, Kalinke U

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2024Scientific Reports14 (1) : 8255

MORITS: An improved method to predict peptides from heterologous proteins that are recognized by the same T-cell receptor

Bruhn M, Spatz M, Kalinke U

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2024Clinical Immunology (orlando, Fla.)260 : 109902

A tetravalent bispecific antibody outperforms the combination of its parental antibodies and neutralizes diverse SARS-CoV-2 variants

Chiyyeadu A, Asgedom G, Bruhn M, Rocha C, Schlegel T, Neumann T, Galla M, Vollmer Barbosa P, Hoffmann M, Ehrhardt K, Ha T, Morgan M, Schoeder C, Pöhlmann S, Kalinke U, Schambach A

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2024The Journal of Infection88 (1) : 57-60

Memory B cells anticipate SARS-CoV-2 variants through somatic hypermutation

Bruhn M, Obara M, Chiyyeadu A, Costa B, Salam A, Ziegler A, Waltl I, Pavlou A, Bonifacius A, Hoffmann M, Graalmann T, Pöhlmann S, Eiz-Vesper B, Schambach A, Kalinke U

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2021Annals of the Rheumatic Diseases80 (12) : 1537-1544

B cell depletion impairs vaccination-induced CD8+ T cell responses in a type I interferon-dependent manner

Graalmann T, Borst K, Manchanda H, Vaas L, Bruhn M, Graalmann L, Koster M, Verboom M, Hallensleben M, Guzmán C, Sutter G, Schmidt R, Witte T, Kalinke U

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