Publikationen

2011Stem Cell Res

Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors.

R Iacob, U Rudrich, M Rothe, S Kirsch, B Maasoumy, N Narain, C M Verfaillie, P Sancho-Bru, M Iken, I Popescu, A Schambach, M P Manns, M Bock

2011Hepatology

MicroRNA-221 regulates FAS-induced fulminant liver failure.

A D Sharma, N Narain, E M Handel, M Iken, N Singhal, T Cathomen, M P Manns, H R Scholer, M Ott, T Cantz

2011PLoS Biol

Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells

G Wu, N Liu, I Rittelmeyer, A D Sharma, M Sgodda, H Zaehres, M Bleidissel, B Greber, L Gentile, D W Han, C Rudolph, D Steinemann, A Schambach, M Ott, H R Scholer, T Cantz

2011J Cell Biol

E:N-cadherin heterodimers define a novel kind of adherens junction connecting certain endoderm-derived normal and tumor cells

B K Straub, S Rickelt, R Zimbelmann, C Grund, C Kuhn, M Iken, M Ott, P Schirmacher, W W Franke

2011J Hepatol

Directed differentiation of murine-induced pluripotent stem cells to functional hepatocyte-like cells.

P Sancho-Bru, P Roelandt, N Narain, K Pauwelyn, T Notelaers, T Shimizu, M Ott, C Verfaillie

2011Biologicals

Taking immunogenicity assessment of therapeutic proteins to the next level.

I C Buttel, P Chamberlain, Y Chowers, F Ehmann, A Greinacher, R Jefferis, D Kramer, H Kropshofer, P Lloyd, A Lubiniecki, R Krause, A Mire-Sluis, T Platts-Mills, J A Ragheb, B M Reipert, H Schellekens, R Seitz, P Stas, M Subramanyam, R Thorpe, J H Trouvin, M Weise, J Windisch, C K Schneider

2011J Virol

N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.

M S Gratz, Y Suezer, M Kremer, A Volz, M Majzoub, K M Hanschmann, U Kalinke, A Schwantes, G Sutter

2011Nat Rev Drug Discov

Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response.

H G Eichler, E Abadie, A Breckenridge, B Flamion, L L Gustafsson, H Leufkens, M Rowland, C K Schneider, B Bloechl-Daum

2011Mol Biotechnol

Comparative analysis of transduced primary human dendritic cells generated by the use of three different lentiviral vector systems.

E Grabski, Z Waibler, S Schule, BP Kloke, LY Sender, S Panitz, K Cichutek, M Schweizer, U Kalinke

2011Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz

Report from the Committee for Advanced Therapies (CAT). Pitfalls on the way from concept to medical treatment with advanced therapy medicinal products.

M Reiss, I C Buttel, C K Schneider